You will inject the medication into the abdomen, thighs, or upper arms
High incidence of metabolically active Brown adipose tissue in healthy adult humans: Effects of cold exposure and adiposity
Eli Lilly and Company press release, 2023

For patients I see in clinic, retatrutide may potentially be a highly impactful future tool to treat their obesity and transform their health trajectory. Commenting on the topline results, Professor Graham Finlayson, chair in psychobiology at the University of Leeds, said it was striking to see retatrutide reaching the weight loss range historically associated with bariatric surgery and that the headline efficacy results are impressive, particularly the proportion of participants reported to achieve very large weight losses. He added: In principle, that broader pharmacology could produce larger effects on body weight and metabolism, although the full peer-reviewed data will be needed to understand the balance between efficacy, tolerability and discontinuation. While this clinical trial did not examine weight regain after stopping retatrutide, other studies have found that discontinuing weight-loss medications such as semaglutide and liraglutide typically results in near-total weight regain within about 18 months

Exercise more The American Diabetes Association (ADA) recommends that adults get at least 2 hours and 30 minutes of moderate-intensity exercise per week